Dicarboxylic acids and derivatives
Medchemexpress LLC UCPH-101 excitatory amino acid transporter subtype 1 inhibitor | 1118460-77-7 | 98.6% | 422.48 | 1 ML
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. This compound is suitable for research applications. It presents as a white to off-white solid.
- Molecular weight: 422.48
- Formula: C27H22N2O3
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US (may vary elsewhere)
- Storage: Powder at -20°C for 3 years or 4°C for 2 years; in solvent at -80°C for 2 years or -20°C for 1 year
- Solubility: In DMSO: ≥ 50 mg/mL (118.35 mM)
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 50mg
CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 50 MG
1,2-Dilauroyl-sn-glycerol is a saturated diacylglycerol that may be involved in second messenger signal transduction. It appears as a white to off-white solid with a molecular formula of C27H52O5 and a molecular weight of 456.70. This product is intended for research use only.
- Purity of 98.0%
- CAS number: 60562-15-4
- Soluble in DMSO (100 mg/mL), requiring ultrasonic for dissolution
- Ships at room temperature within the continental US
- Recommended storage for powder: -20°C for 3 years
- Recommended storage for in-solvent solutions: -80°C for 6 months, or -20°C for 1 month (aliquot and store to prevent inactivation from repeated freeze-thaw cycles)
- Related to metabolic enzymes/proteases and endogenous metabolites
- Acts as an inhibitor
Apexbio Technology LLC CAL-101 (Idelalisib, GS-1101) 870281-82-6 100mg
CAL-101 (Idelalisib GS-1101 CAS 870281-82-6) is a selective inhibitor targeting the p110 isoform of phosphatidylinositol 3-kinase (PI3K) an enzyme involved in signaling pathways critical for proliferation and survival of malignant B cells By inhibiting PI3K p110 CAL-101 reduces PI3K-mediated phosphorylation of Akt and other downstream factors leading to enhanced PARP cleavage and caspase activation ultimately inducing apoptosis in malignant B cells CAL-101 has been demonstrated to counteract survival signals initiated by molecules such as CD40 ligand (CD40L) TNF- and fibronectin This agent is valuable in investigating B-cell malignancies
Medchemexpress LLC Lauroyl-L-carnitine-d9 chloride | 2245711-25-3 | MFCD34676545 | 98.0% | 389.02 g/mol | C19H29D9ClNO4 | 5 MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled chloride salt of lauroyl-L-carnitine supplied for analytical and tracer applications. It is intended for use as a stable-isotope internal standard in bioanalytical, pharmacokinetic, and tracer studies where mass spectrometry differentiation is required.
- Stable isotope labeled internal standard for mass spectrometry
- Deuterated (d9) for clear mass separation from native compound
- High purity (98.0%) suitable for analytical workflows
- Chloride salt form for compatibility with common assays
- Supplied in a 5 mg quantity for small-scale analyses
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻1 | C29H58NO8P | 50 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with lauric (12:0) acyl chains. It is commonly used as a lipid component for preparing liposomes and for studies of membrane composition in biochemical and biophysical research.
- High purity suitable for research applications.
- Useful for liposome synthesis and membrane composition studies.
- Available in multiple small pack sizes for laboratory use.
- Contains lauric (12:0) acyl chains for defined lipid composition.
- Molecular weight 579.75 g·mol⁻1 and formula C29H58NO8P for accurate formulation.
Medchemexpress LLC Caveolin-1 (82-101) amide (human, mouse, rat) | 2757108-69-1 | 99.1% | 2516.85 | 10 MG
Caveolin-1 (82-101) amide (human, mouse, rat) is a peptide that reverses aging-associated deleterious changes in multiple organs. It inhibits tyrosine kinases.
- Reverses aging-associated deleterious changes in multiple organs.
- Inhibits tyrosine kinases.
- For research use only.
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻¹ | C29H58NO8P | 100 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a phosphatidylethanolamine derivative bearing two lauroyl (C12:0) acyl chains. It is a research-grade lipid commonly used for liposome formulation and membrane model studies; typical properties include a molecular weight of 579.75 g·mol⁻¹ and high purity (98.0%).
- Phosphatidylethanolamine lipid with two lauroyl (C12:0) chains.
- Suitable for liposome synthesis and membrane model studies.
- High purity (98.0%) for research applications.
- Molecular formula C29H58NO8P and molecular weight 579.75 g·mol⁻¹.
TARGETMOL CHEMICALS INC GLYH-101 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. purity: 98%
Medchemexpress LLC JI-101 (hydrochloride) | 2514957-81-2 | 502.79 | 100 MG
JI-101 (hydrochloride) | 2514957-81-2 | 502.79 | 100 MG
Medchemexpress LLC 1,2-Dilauroyl-sn-glycerol | 60562-15-4 | 98.0% | 100 MG
1,2-Dilauroyl-sn-glycerol is identified as a saturated diacylglycerol that might be involved in second messenger signal transduction. It is available as a solid, appearing white to off-white, with a molecular weight of 456.70 and the chemical formula C27H52O5. This compound is intended strictly for research purposes.
- Saturated diacylglycerol.
- May play a role in second messenger signal transduction.
- Available in solid form.
- Appears white to off-white.
- Strictly for research use.
- High purity of 98.0%.
![Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000229462.png-250.jpg)
Medchemexpress LLC O=C([C@]1(CO1)CO[Si](C)(C)C(C)(C)C)[C@H](CC(C)C)NC([C@H](C)NC(CCCCCC)=O)=O | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 5 MG
UK-101 is a selective immunoproteasome β1i (LMP2) inhibitor for laboratory research. It shows reported potency with an IC50 of about 104 nM and is supplied as a high-purity solid suitable for in vitro studies; recommended solvent is DMSO.
- Selective immunoproteasome β1i (LMP2) inhibitor with IC50 ≈104 nM.
- High purity (≈99.6%).
- Available in small research quantities, e.g., 5 mg.
- Recommended solvent: DMSO for dissolution.
- Powder storage: -20°C (3 years) or 4°C (2 years); solutions: -80°C (6 months).
- For research use only; not for human or clinical use.
![Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | C22H19FN6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261386.png-250.jpg)
Medchemexpress LLC N-(2-(1H-indol-3-yl)ethyl)-5-(5-fluoropyridin-3-yl)-3-methylpyrazolo[1,5-a]pyrimidin-7-amine | 2247950-73-6 | 98.0% | C22H19FN6 | 10MG
KYN-101 is a small-molecule, selective, orally active antagonist of the aryl hydrocarbon receptor (AHR) supplied for laboratory research. It reduces CYP1A1 mRNA expression and has demonstrated anti-cancer activity in preclinical studies, making it suitable for mechanistic studies of AHR signaling and oncology research.
- Selective AHR inhibition with reported nanomolar potency.
- Orally active in preclinical models.
- Reduces CYP1A1 mRNA expression in cellular assays.
- Useful for mechanistic studies of AHR signaling and cancer biology.
- Available as solid and ready-to-use DMSO solutions for assay setup.
- High purity suitable for research applications.
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 1 MG
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10, alleviating Crohn's-like colitis. It demonstrates anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Reverses decrease in target gene IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.81% | 10 G
Sodium lauroyl glutamate is an anionic amino acid surfactant. It has been noted for its potential to cause irritant contact dermatitis, but also for its possible anti-irritating potential when part of a surfactant mixture on human skin. As a mild surfactant, it is primarily utilized in cleaning products. It has a pH value of 5.41 and demonstrates low irritation to the nude mouse skin.
- Anionic amino acid surfactant
- Used in cleaning products
- Exhibits low irritation to nude mouse skin in vitro
- For research use only; not sold to patients