Dicarboxylic acids and derivatives
Medchemexpress LLC Ji-101 | 900573-88-8 | MFCD26142530 | 99.8% | 466.33 | C22H20BrN5O2 | 10 MG
JI-101 is an orally available multi-kinase inhibitor that targets VEGFR2, PDGFRβ, and EphB4 and has demonstrated potent anti-cancer activity. It is provided as a white to off-white solid powder for research use and is commonly supplied in a 10 mg pack.
- Orally available multi-kinase inhibitor active against VEGFR2, PDGFRβ, and EphB4.
- High purity (99.78%).
- Molecular formula C22H20BrN5O2; molecular weight 466.33 g/mol.
- White to off-white solid, soluble in DMSO at ≥ 100 mg/mL.
- Intended for research use only; not for human administration.
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | 98.1% | 1 ML
Lauroyl-L-carnitine chloride is an orally active metabolite that significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This product is for research use only.
- Orally active metabolite
- Reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes of TNBS mice
Medchemexpress LLC Vnt-101 | 2894060-67-2 | 456.41 | C21H23F3N2O6 | 10 MG
VNT-101 is a small-molecule, orally active inhibitor of influenza A virus nucleoprotein (NP) oligomerization. It disrupts NP-NP protein-protein interactions to destabilize the viral ribonucleoprotein complex and has been used in vitro and in vivo to study antiviral activity across multiple influenza A subtypes.
- Disrupts nucleoprotein oligomerization to inhibit viral replication.
- Orally bioavailable small molecule suitable for in vivo studies.
- Demonstrated activity against multiple influenza A subtypes.
- Molecular weight 456.41 and molecular formula C21H23F3N2O6.
- CAS number 2894060-67-2 for substance identification.
- Supplied as a solid for research use with supporting characterization data.
Medchemexpress LLC Lauroyl-L-carnitine-d9 chloride | 2245711-25-3 | MFCD34676545 | 98.0% | 389.02 g/mol | C19H29D9ClNO4 | 5 MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled chloride salt of lauroyl-L-carnitine supplied for analytical and tracer applications. It is intended for use as a stable-isotope internal standard in bioanalytical, pharmacokinetic, and tracer studies where mass spectrometry differentiation is required.
- Stable isotope labeled internal standard for mass spectrometry
- Deuterated (d9) for clear mass separation from native compound
- High purity (98.0%) suitable for analytical workflows
- Chloride salt form for compatibility with common assays
- Supplied in a 5 mg quantity for small-scale analyses
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 g/mol | C25H48N2O5Si | 25 MG
UK-101 is a potent, selective immunoproteasome β1i (LMP2) inhibitor intended for research use. It has a reported IC50 of 104 nM against LMP2, with significant selectivity over the constitutive β1c and β5 proteasome subunits. UK-101 is used in cell-based studies to induce apoptosis and to investigate immunoproteasome function and cancer-related pathways. Supplied as a powder with recommended storage conditions to preserve stability.
- Potent LMP2 (β1i) inhibitor with IC50 ≈ 104 nM.
- Selective over proteasome β1c and β5 subunits.
- Induces apoptosis in cell-based assays.
- High purity suitable for biochemical and cellular studies.
- Supplied as powder with recommended storage for long-term stability.
Medchemexpress LLC 4H-1-Benzopyran-3-carbonitrile, 2-amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(1-naphthalenyl) | 1118460-77-7 | 98.61% | 422.48 | 100 MG
UCPH-101 is a potent excitatory amino acid transporter subtype 1 (EAAT1) inhibitor, demonstrating an IC50 of 0.66 μM. This compound is intended for research applications only and is not suitable for patient use.
- Inhibits EAAT1 anion currents with a KD value of 0.34±0.03 μM (Hill=1.3±0.13, n≥9).
- Causes a small but significant decrease in total expression levels of HA-EAAT1 and HA-GLAST in cells preincubated with 100 μM UCPH-101 (p=0.048).
Medchemexpress LLC VH 101, acid | 2408341-97-7 | 98.8% | 574.66 | C28H35FN4O6S | 10 MG
VH 101, acid is a functionalized von Hippel-Lindau (VHL) E3 ligase ligand developed for PROTAC research and conjugation chemistry. The molecule includes an E3 ligase recognition motif and an alkyl linker terminating in a primary amine, facilitating attachment to target protein ligands.
- Designed for use as a VHL E3 ligase ligand in PROTAC development.
- Alkyl linker with terminal amine enables straightforward conjugation chemistry.
- High reported purity suitable for research applications.
- Supplied in small research-scale quantities for synthetic work and assay testing.
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻1 | C29H58NO8P | 50 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with lauric (12:0) acyl chains. It is commonly used as a lipid component for preparing liposomes and for studies of membrane composition in biochemical and biophysical research.
- High purity suitable for research applications.
- Useful for liposome synthesis and membrane composition studies.
- Available in multiple small pack sizes for laboratory use.
- Contains lauric (12:0) acyl chains for defined lipid composition.
- Molecular weight 579.75 g·mol⁻1 and formula C29H58NO8P for accurate formulation.
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 5 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment with excitation/emission at 411 nm/512 nm. It exhibits solid-state fluorescence and is available as a commercial colorant. This product is for research use only and not sold to patients.
- Yellow bis-azomethine pigment
- Exhibits solid-state fluorescence
- Excitation/emission: 411 nm/512 nm
- Available as a commercial colorant
![Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236923.png-250.jpg)
Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG
LEI-101 hydrochloride is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist supplied for research use. It demonstrates strong functional activity at human CB2 receptors with substantially lower affinity for CB1 and minimal hERG binding, suitable for in vitro and in vivo pharmacology studies.
- Purity 99.4%.
- Reported activity pEC50 = 8 for human CB2.
- Approximately 100-fold selectivity for CB2 over CB1.
- Low hERG interaction (pKi < 4).
- Soluble in DMSO; available as dry powder and 10 mM solution in DMSO.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | 99.1% | 434.49 g/mol | C24H26N4O4 | 1 ML
CUDC-101 is a small-molecule inhibitor that targets histone deacetylases (HDAC) and receptor tyrosine kinases EGFR and HER2. It is intended for research use in studies of signaling pathways, anti-proliferative activity, and preclinical cancer models. The compound is supplied as a high-purity reagent suitable for in vitro experiments.
- Multi-target HDAC, EGFR, and HER2 inhibition
- High purity suitable for research applications
- Available as a ready-to-use 10 mM solution in DMSO (1 mL)
- Confirmed molecular formula and molecular weight for analytical workflows
- Intended for in vitro and preclinical research use
TARGETMOL CHEMICALS INC PKUMDL-LC-101-D04 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4) a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 uM in a cell-free assay and at a concentration of 61 uM in wild-type but not Gpx4-/- mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 uM) reduced cholesterol peroxide-induced MEF death. purity: 98%
Medchemexpress LLC Lei 101 hydrochloride | 2250025-91-1 | 99.4% | 508.99 g/mol | C23H26ClFN4O4S | 10MM 1ML
LEI-101 hydrochloride is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist used for receptor pharmacology and preclinical research. It is provided in both solid form and as a ready-to-use DMSO solution to support biochemical and cellular assays.
Apexbio Technology LLC GlyH-101 328541-79-3 10mg
GlyH-101 (CAS 328541-79-3) is a cell-permeable glycinyl hydrazone derivative that acts as a selective inhibitor of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel exhibiting a Ki of 1 4 M By blocking CFTR-mediated chloride transport GlyH-101 serves as a valuable tool for investigating CFTR function in epithelial physiology and pathophysiology as well as for studying mechanisms underlying cystic fibrosis and related disorders involving chloride ion dysregulation
Medchemexpress LLC UCPH-101 excitatory amino acid transporter subtype 1 inhibitor | 1118460-77-7 | 98.6% | 422.48 | 1 ML
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. This compound is suitable for research applications. It presents as a white to off-white solid.
- Molecular weight: 422.48
- Formula: C27H22N2O3
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US (may vary elsewhere)
- Storage: Powder at -20°C for 3 years or 4°C for 2 years; in solvent at -80°C for 2 years or -20°C for 1 year
- Solubility: In DMSO: ≥ 50 mg/mL (118.35 mM)