Dicarboxylic acids and derivatives
Apexbio Technology LLC AS 101 106566-58-9 10mg
AS 101 (CAS 106566-58-9) chemically known as ammonium trichloro(dioxoethylene-O O -)tellurate is a non-toxic immunomodulatory small molecule that acts primarily by inhibiting interleukin-10 (IL-10) signaling In cell-based studies AS 101 reduces IL-10 production and suppresses mesangial cell proliferation in a dose-dependent manner It has been shown to decrease tyrosine phosphorylation and nuclear translocation of STAT3 correlating with inhibition of IL-10 activity AS 101 stimulates IL-2 secretion and enhances immune cell function in both human and murine models In animal studies systemic administration confers bone marrow-sparing effects during chemotherapy mitigates alopecia enhances survival in sepsis models and modulates cytokine production These properties support its utility in investigating immune regulation and potential therapeutic interventions targeting cytokine-mediated pathologies
Apexbio Technology LLC PKUMDL-LC-101-D04 2143896-83-5 10mg
PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
Medchemexpress LLC Ethyl Lauroyl Argina 5g
Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative[1]
![Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247159.png-250.jpg)
Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG
CUDC-101 is a small-molecule research compound that concurrently inhibits histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2. It is used in preclinical cancer research to study combined epigenetic and kinase-targeted therapies.
- Potent inhibition of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM.
- Contains a hydroxamic acid moiety associated with HDAC activity.
- High purity (>98.0%) suitable for research applications.
- Soluble in DMSO at 25 mg/mL (approximately 57.54 mM; may require ultrasonic agitation).
- Molecular formula C24H26N4O4 and molecular weight 434.49 g/mol.
Medchemexpress LLC Sulforhodamine 101 DHPE | 187099-99-6 | >95.0% | 1381.84 | C74H117N4O14PS2 | 1MG
Sulforhodamine 101 DHPE is a red fluorescent phospholipid probe created by conjugating dipalmitoyl phosphoethanolamine to sulforhodamine 101. It readily incorporates into lipid bilayers and is used for membrane imaging, monitoring probe colocalization in liposomes, and detecting protein-ligand interactions on supported bilayers. The dye exhibits excitation/emission peaks near 586/605 nm and is supplied as a powder with recommended cold storage.
Medchemexpress LLC Uk-101 | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 10 MG
UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit used as a biochemical probe to study immunoproteasome activity and apoptosis-related pathways.
- Potent LMP2 inhibition (IC50 ≈ 104 nM).
- High selectivity versus β1c and β5 subunits.
- High purity suitable for research use (≈99.6%).
- Soluble in DMSO (≈7.3 mg/mL); may require warming or sonication.
- Supplied in small quantities appropriate for laboratory assays.
- Commonly used in biochemical assays and apoptosis research.
Medchemexpress LLC 7-((4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 50 MG
CUDC-101 is a small-molecule research inhibitor of histone deacetylases (HDACs), epidermal growth factor receptor (EGFR), and HER2, used in preclinical cancer research to assess antiproliferative and target-specific effects.
- Potent inhibitor of HDAC, EGFR, and HER2 with low-nanomolar activity.
- Demonstrates broad antiproliferative effects across cancer cell lines.
- Supplied as a light yellow to yellow powder for laboratory use.
- High purity suitable for research applications (reported ≥98% by HPLC).
- Available in small-mass packaging for research workflows.
- Molecular weight 434.49 g/mol.
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.06% | 50 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment that exhibits solid-state fluorescence with excitation/emission at 411 nm/512 nm. This product is available as a commercial colorant.
- Yellow bis-azomethine pigment
- Excitation/emission: 411 nm/512 nm
- Exhibits solid-state fluorescence
- Available as a commercial colorant
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.1% | 100 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment that exhibits solid-state fluorescence and is available as a commercial colorant.
- Exhibits solid-state fluorescence
- Available as a commercial colorant
- Yellow bis-azomethine pigment
- Excitation/emission: 411 nm/512 nm
Medchemexpress LLC Rhodamine 101 hydrochloride | 64339-18-0 | 95.0% | 563.51 | 25 MG
Rhodamine 101 hydrochloride is a fluorescent dye. It is known for its bright fluorescence and specific excitation and emission characteristics.
- Exhibits bright fluorescence
- Excitation maxima at 565 nm
- Emission maxima at 595 nm.
Medchemexpress LLC Rhodamine 101 hydrochloride | 64339-18-0 | MFCD00210089 | >=95% | 563.51 | 5 MG
Rhodamine 101 chloride (Rhodamine 640 chloride) hydrochloride is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.
- For research use only.
- We do not sell to patients.
Apexbio Technology LLC Sulforhodamine 101 60311-02-6 25mg
Sulforhodamine 101 (60311-02-6) is a red-emitting fluorescent dye primarily utilized as a selective marker for astrocytes Sulforhodamine 101 selectively accumulates in astrocytes enabling differentiation from surrounding neuronal populations In neurobiological studies using live tissue imaging including acute brain slice preparations the dye facilitates visualization of astroglial cell morphology and cellular dynamics Based on these properties Sulforhodamine 101 holds research potential in the study of astrocyte-specific responses morphological characteristics and cell cell interactions within neuronal tissues
Medchemexpress LLC PKUMDL-LC-101-D04 500mg | 2143896-83-5 | 378.93 g·mol⁻¹ | C14H23ClN4O2S2 | 500 MG
PKUMDL-LC-101-D04 is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used in research on ferroptosis, lipid peroxidation, and inflammation. It increases GPX4 enzymatic activity in cell-free and cellular assays (reported pEC50 = 4.7) and protects cells from cholesterol peroxide-induced toxicity.
- Allosteric activator of GPX4, reported pEC50 = 4.7.
- Increases GPX4 activity to ~150% in cell-free and cellular extracts at reported concentrations.
- Demonstrated inhibition of ferroptosis and protection against lipid peroxide-induced cell death.
- Molecular weight ~378.93 g·mol⁻¹ and chemical formula C14H23ClN4O2S2.
- Supplied as a high-purity research chemical suitable for biochemical and cellular assays.
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 1 MG
UK-101 is a selective small-molecule inhibitor of the immunoproteasome β1i (LMP2) subunit used in biochemical and cellular research to probe immunoproteasome function and induce apoptosis in certain cancer models.
- Selective LMP2 (β1i) inhibitor with reported IC50 of 104 nM.
- Shows ~144-fold selectivity versus β1c and ~10-fold versus β5.
- High reported purity (99.58%) suitable for research applications.
- Molecular weight 484.74 g·mol⁻¹ and formula C25H48N2O5Si.
- Soluble in DMSO and supplied in small research quantities, including 1 mg packs.
Medchemexpress LLC AVN-101 hydrochlorid 25mg | 1061354-48-0 | 340.89 | C21H25ClN2 | 25 MG
AVN-101 hydrochloride is the hydrochloride salt of a brain-penetrant small molecule antagonist of serotonin (5-HT) receptors, supplied for preclinical and in-vitro research. It is provided as a solid with reported high purity for analytical and biological assays.
- Potent antagonist of 5-HT receptor subtypes (5-HT7, 5-HT6, 5-HT2A, 5-HT2C).
- High purity: 99.59%.
- Molecular formula C21H25ClN2; molecular weight 340.89.
- Available in small research pack sizes, including 25 MG.
- Provided as hydrochloride salt to improve solubility for assay preparation.
- For research use only; not for human or veterinary use.